Hilma Biocare Testosterone Enanthate 10 ml vial (250 mg/ml)

Testosterone Enanthate

Testosterone plays a crucial role in the growth and development of male sex organs and maintains secondary sexual traits. This powerful hormone impacts the prostate, testes, seminal vesicles, penis, and scrotum while significantly contributing to body growth. Although classified as an androgenic hormone, it also exhibits anabolic features. Its administration can enhance protein synthesis and promote a positive nitrogen balance when accompanied by a rich, low-calorie diet. Furthermore, testosterone aids in mildly stimulating red blood cell production by promoting EPO synthesis from the kidneys, enhancing oxygen-carrying capacity. However, long-term use of testosterone can inhibit gonadotropin release from the pituitary gland through negative feedback mechanisms, potentially affecting spermatogenesis at elevated doses.

Dosage

Testosterone enanthate (Delatestryl) dissolves slowly post-intramuscular injection, thus it should be used no more than once or twice monthly. This formulation is an esterified preparation intended solely for intramuscular administration, prolonging its action. It appears as a colourless to slightly yellow sesame oil suspension. For medical use, a dose of 250-500mg is recommended monthly.

Indications

Delatestryl is prescribed for conditions associated with testosterone deficiency or absence, including:

• Primary hypogonadism resulting from testicular injury
• Hypogonadism due to pituitary failure in releasing gonadotropins
• Delayed puberty

In women with breast cancer, testosterone can mitigate estrogen effects and inhibit further spread, serving as an alternative to ovariectomy. Usually, long-term therapy is necessary to achieve adequate development of secondary sexual characteristics amidst testosterone deficiency.

Duration

Treatment duration with testosterone enanthate varies based on individual factors, including age, sex, diagnosis, and side effects. Generally, the drug is well tolerated when prescribed correctly. Delatestryl should be injected into gluteal muscles, avoiding subcutaneous injections, and the injection site should be rotated to prevent abscess formation. It is advisable to limit the monthly dosage to less than 1000 mg, given its prolonged effects. Rarely is it administered biweekly. The formulation should be inspected prior to injection—particles or clumping indicates expiration or inactivity. Typical treatment spans 4-6 months, with storage at room temperature recommended.

Bodybuilders

Numerous bodybuilders utilize Delatestryl primarily off-season due to its extended presence in the body; however, its use during active sports seasons is discouraged. This compound possesses notable anabolic and androgenic capabilities, albeit effects may not be evident for 3-4 weeks. Many bodybuilders combine it with other hormones like GH/thyroxine. As testosterone can convert to estrogen in fat tissues, it may lead to breast enlargement and water retention in some users. Dosages aimed at enhancing muscle mass typically range from 250-1000 mg per week; beginners are advised to start with lower doses to mitigate potent side effects. Muscle mass increase is gradual, and heightened red blood cell production often improves performance during rigorous training. Testosterone enanthate is favored for its availability and benefits, offering enhanced health, athletic performance, and promoting a positive nitrogen balance. Some reports suggest significant fat reduction and muscle gain, with evidence from the World Sport Agencies indicating effectiveness without detectable traces in urine during initial weeks. Water retention may be substantial, with some using diuretics for management. To counteract potential breast enlargement, antithesis drugs like Arimidex or Tamoxifen are cycled alongside testosterone. Standard cycles last 4-6 weeks, followed by a brief break, during which Arimidex may be used to flush the system.

Women

All testosterone derivatives can induce virilizing effects with prolonged use in women, such as deepening voice, excessive hair growth, irregular menstrual cycles, mood changes, and clitoral enlargement. Immediate discontinuation is recommended upon any signs of virilization since some effects may not be reversible even after ceasing use.

Side Effects

Similar to all anabolic steroids, testosterone enanthate has potential side effects, although most are mild and manageable. Common side effects observed after 3-4 months of therapy include:

• Bleeding irregularities
• Virilizing effects
• Voice deepening
• Clitoral enlargement
• Gynaecomastia
• Painful erections
• Acne, oily skin, hair loss
• Water retention
• Nausea, jaundice, vomiting
• Rare liver cancer
• Mental health changes (depression, anxiety, headaches)
• Increased cholesterol levels

While many side effects can reverse post-therapy, breast enlargement and certain virilizing effects may persist. Co-administering estrogens to reduce virilization risks may not prove beneficial. In children, testosterone administration requires close monitoring, as it may accelerate bone maturation without promoting compensatory linear growth, leading to potential anatomical distortions, particularly in the jaw and facial structure.

Warnings

Caution is advised in individuals with conditions such as:

• Breast cancer or hypercalcemia
• Liver dysfunction
• Prostate cancer
• Cardiovascular issues

Some users report dry cough or breathing difficulties post-injection, potentially linked to oil composition or impurities. Regular checks of liver enzymes and blood hematocrit levels are recommended for anyone using testosterone to confirm they remain within normal limits.

Recognition

Testosterone enanthate’s extended half-life leads to detectable urine traces long after use cessation. Current testing methods can identify testosterone or its metabolites in urine 3-4 weeks after discontinuation; furthermore, traces may be found in hair 2-4 months post-use. However, testing for testosterone enanthate is not foolproof, with about 50% of users possibly overlooked based on testosterone/epitestosterone ratios.

Cost

Legal acquisition of testosterone enanthate poses challenges, prompting many bodybuilders to source it from the black market. Generic formulations are widely available in Europe and Mexico, with costs for a 250 mg vial ranging from $10 to $20. Increased scrutiny by the DEA over two decades has led to counterfeit products being circulated, placing the onus on buyers to ensure quality.