Somatrop-Lab Nandrolone Phenylpropionate 10 ml vial (100 mg/ml)

Nandrolone Phenylpropionate

Nandrolone phenylpropionate is an injectable anabolic steroid variant of nandrolone. It’s closely related to Deca-Durabolin, which utilizes the slower-acting nandrolone decanoate. The primary distinction lies in their release rates; while nandrolone decanoate is effective for about three weeks, nandrolone phenylpropionate acts for roughly one week. Consequently, Deca-Durabolin can be administered every two to three weeks, whereas Durabolin is typically injected every few days to weekly. Athletes and bodybuilders favor both drugs for their capacity to enhance strength and lean muscle mass without significant estrogenic or androgenic effects.

Structural Characteristics

Nandrolone phenylpropionate features a propionic phenyl ester linked to the 17-beta hydroxyl group, allowing for slower absorption compared to free steroids. Once in circulation, the ester is cleaved to produce active nandrolone. This design offers prolonged therapeutic effects, allowing for less frequent injections. The initial nandrolone release peaks within 24 to 48 hours after deep intramuscular injection, decreasing towards baseline in about a week.

Side Effects (Estrogenic)

Nandrolone’s estrogen conversion is relatively low, approximately 20% compared to testosterone. While the liver can convert nandrolone into estradiol, its conversion is significantly less in various tissues, reducing the risk of estrogenic side effects. Higher doses may lead to side effects like water retention and gynecomastia. In such cases, an anti-estrogen, like clomiphene citrate or tamoxifen citrate, or an aromatase inhibitor, such as Arimidex (anastrozole), can help mitigate these effects, although aromatase inhibitors may be pricier and influence blood lipids.

Side Effects (Androgenic)

Despite its classification as an anabolic steroid, nandrolone can produce androgenic effects, especially at higher doses, including oily skin, acne, and hair growth. Women using this compound might experience virilization symptoms. Nandrolone’s androgenic activity is lower compared to steroids like testosterone, which means there’s a higher threshold for significant androgenic side effects. However, it can still suppress libido in males when not combined with another androgen.

Side Effects (Hepatotoxicity)

Nandrolone is not c-17 alpha alkylated, indicating minimal hepatotoxic risk in healthy individuals.

Side Effects (Cardiovascular)

Anabolic steroids can adversely impact cholesterol levels, reducing HDL and increasing LDL, contributing to arteriosclerosis risk. Research shows a significant decrease in HDL with nandrolone decanoate but still less impactful than c-17 alpha alkylated steroids. Other potential cardiovascular issues include negative effects on blood pressure and triglyceride levels, increasing risks of heart disease.

Side Effects (Testosterone Suppression)

All anabolic steroids typically suppress natural testosterone production. Research indicates substantial decreases in serum testosterone levels during nandrolone decanoate therapy due to its progestational activity. Testosterone levels should normalize within 2 to 6 months post-therapy, although abuse can lead to prolonged hypogonadotrophic hypogonadism.

Administration (Men)

For anabolic effects, dosage recommendations started at 25 to 50mg weekly for 12 weeks. For physique enhancement, doses range from 200 to 400mg weekly in cycles lasting 8 to 12 weeks, often divided into two separate applications due to the fast-acting nature of the phenylpropionate ester.

Administration (Women)

Dosages for women typically mirror those for men at 25 to 50mg weekly for 12 weeks. For physique enhancement, a dosage of 50mg weekly, given as a single injection for 4 to 6 weeks, is common. Higher doses or extended use carry the risk of androgenic side effects, and discontinuation is advised upon initial signs of virilization to prevent irreversible effects.